The binding principle is that while the seriousness of an offence alone is insufficient to deny bail, when considered cumulatively with the nature of the allegations (premeditated murder in aggravatory circumstances), the strength of the state case, the likely lengthy sentence or capital punishment if convicted, and the real risk of absconding, compelling reasons can exist to justify continued detention under section 50 of the Constitution. The admission of an applicant to bail would be denied where it would undermine or jeopardize the objective or proper functioning of the criminal justice system, including when the combination of serious charges, strong evidence, and likelihood of severe punishment creates a real inducement to abscond.