In bail applications, where an accused faces serious charges (wildlife crimes and illegal firearms possession) that carry lengthy prison sentences, and where there is a strong prima facie case including arrest at the scene with weapons of war (AK-47s), evidence of attempted flight at arrest, and potential for interference with ongoing investigations, the cumulative effect of these factors can establish that release on bail would prejudice the interests of justice under section 117 of the Criminal Procedure and Evidence Act. The court must consider each case on its merits, weighing the presumption of innocence and right to liberty against factors indicating flight risk and potential undermining of the criminal justice system. Where the temptation to abscond is real given the gravity of charges and likely sentences, and where bail conditions cannot adequately restrain the risk of interference with investigations, refusal of bail does not amount to anticipatory punishment but is justified in the interests of justice.