When assessing expert medical evidence on cause of death in criminal proceedings, courts must apply the judicial measure of proof (balance of probabilities) and not the scientific measure of proof (scientific certainty). Expert witnesses may assess likelihood in terms of scientific certainty, but courts must assess where the balance of probabilities lies on a review of the whole evidence. Evidence of an accused's mendacity and guilty consciousness cannot, without proof of an unlawful killing, establish the actus reus of murder beyond reasonable doubt. When applying inferential reasoning, the inference of guilt must be consistent with all proved facts, and if the evidence establishes that the deceased probably died of natural causes, an inference of unlawful killing cannot reasonably be drawn, regardless of evidence showing guilty consciousness.