A medical practitioner is not negligent if he or she acts in accordance with a practice accepted as proper by a responsible, reasonable and respectable body of medical opinion, even where another equally reasonable body of medical opinion would have acted differently. Where conflicting medical expert opinions exist, a court must evaluate whether each opinion has a logical basis and whether, in forming their views, the experts directed their minds to the question of comparative risks and benefits and reached a defensible conclusion. An expert opinion that is not capable of withstanding logical analysis may be rejected as not reasonable or responsible. The mere fact that an adverse medical outcome occurs (such as a pressure sore developing) does not constitute prima facie evidence of negligence. In cases involving critically ill patients, clinical judgments weighing the risks of intervention against potential harm must be assessed by reference to whether they represent a reasonable and respectable body of medical opinion, not by the court's preference between competing views.